Biological materials, which have risen from hundreds of million years of evolution, have offered inspirations in the designs of novel materials that fulfill various functional purposes. In this study, we developed a novel facile methodology for fabricating multi-functional self-cleaning surfaces by atmospheric pressure plasma technique and surface modification. The synthesized coating displayed high transparency, high temperature durability and mechanical stability. The performances of self-cleaning and oil-water separation were successfully demonstrated. Moreover, we discovered that diatomite, a silica-based, nano-porous bio-material, serves as a good candidate for improving the performance of oil-water separation. Through the freeze casting technique, the synthesized hierarchically porous plate exhibited underwater superoleophobicity. Furthermore, the plate exhibits excellent environmental stability under a series of harsh environments, including strong acidic, brine, and hot water. To recapitulate, we report two cost-effective, eco-friendly, feasible, and robust methods for synthesizing multifunctional surfaces and interfaces which can be widely applied in various fields.