Ductile fracture limits the performance, safety, reliability and manufacturability of a variety of engineering components and structures; for example, crash worthiness of automobiles, integrity of pipelines, blast resistance of ships and airplane cargo holds, and manufacturability of sheet metal components. The mechanism of ductile fracture in engineering metals and alloys involves nucleation, growth and coalescence of micron scale voids. The aim of this work is to isolate the key features of controlled distributions of void nucleating particles in a material and quantify its effects on crack path and crack growth resistance. Here, finite element, finite deformation calculations are carried out using a constitutive framework for progressively cavitating ductile solids. The material is modeled as an isotropic hardening viscoplastic solid with three dimensional controlled distributions of void nucleating particles. Our results indicate that by controlling the particle distribution we can control the crack path and maximize the crack growth resistance.