|About this Abstract
||2018 TMS Annual Meeting & Exhibition
||Powder Metallurgy of Light, Reactive and Other Non-ferrous Metals
||Powder Metallurgy Porous Ti-10Mo Alloy for Orthopedic Applications: Structure Characterization, Mechanical Properties, Vitro Cytotoxicity and Vivo Osteointegration
||Xin Lu, Wei Xu, Xuanhui Qu
|On-Site Speaker (Planned)
Porous binary Ti-10Mo alloy has been fabricated by space holder method from elemental powders. The pore characteristics, microstructure and mechanical properties of the fabricated alloys were investigated, followed by a detailed assessment of its cytotoxicity in vitro and osseointergration properties in vivo. The sintered alloys are characterized by typical Widmanstatten structure, and their porosity and average pore size can be controlled in the range of 50.58-66.93% and 112.2-435.1μm, respectively. Ti-10Mo alloy with 63.43% porosity exhibits superior mechanical properties for implanting with an elastic modulus of 2.9GPa, and a yield strength of 127.5MPa. The cell viability in alloy-conditioned medium shows a distinctly higher than those in the blank group, suggesting non-toxic and good biological characteristics of alloys. The samples have been implanted into Sprague-Dawley rat’s femur. After 8 weeks, the implants are surrounded by new bone tissue with no inflammations to any noticeable extent observed at implantation site.
||Planned: Supplemental Proceedings volume