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Meeting Materials Science & Technology 2016
Symposium Next Generation Biomaterials
Presentation Title In Vivo Evaluation of Novel Amorphous Silicon Oxynitrophosphide Implant Coatings for Rapid Bone Healing
Author(s) Venu G Varanasi, Azhar Ilyas, Pranesh Aswath, Harry Kim, Phillip Kramer
On-Site Speaker (Planned) Venu G Varanasi
Abstract Scope Structurally unstable fracture sites require permanent or semi-permanent bone implants that are typically made of titanium (Ti) or other inert metals. The material properties of these fixative devices play significant role in bone healing. A material that that reacts favorably and adheres well to the in-vivo bone environment is critical for rapid bone healing. Here, we propose the use of nanofabricated amorphous silicon oxynitrophosphide (Si-O-N-P) as an overlay onto metal implants in load-bearing bone defect applications. We will exhibit the mechanical and chemical characterization of nanofabricated device to assess its adhesion to the underlying metal/metal oxide. We will also reveal its osteoinductive behavior when placed in biological environment in-vitro and craniofacial defects in-vivo. The interaction of the elemental components at bone-SiONP/TiO2/Ti interface will be presented and discussed. A novel antioxidant role will be revealed that will illustrate the connection between immunological and pathways that enhance bone healing.
Proceedings Inclusion? Undecided

OTHER PAPERS PLANNED FOR THIS SYMPOSIUM

A New Method to Produce Macroporous Bone Cement
Additive Manufacturing of Functionally Graded Titanium Alloys for Biomedical Devices
Additive Manufacturing of Microscale and Nanoscale Structures for Medical Devices
Advanced Freeze Casting for Mimetic Bone and Biomaterials
Bioactive Glass Hydrogel Composites Potential for Skeletal Tissue Repair
Bioactive Materials Releasing Biologially Active Ions: Li and Nb Doped 45S5 Bioactive Glasses
Biomimetic Coatings Using Simulated Body Fluids: A Status Review
Comparison of Annealing and Hot Isotactic Pressing for Post Processing Heat Treatment of Direct Metal Laser Sintered Ti6Al4V
Development of Novel Implants with Embedded Therapeutics Using Additive Manufacture
Development of Osseointegrated Implants and Antimicrobial Technologies
Direct Ink Writing of Bioactive Silica-bonded Calcite Scaffolds from a Preceramic Polymer and Fillers
Effect of Pretreatment on Microarc Oxidation of Magnesium: Characteristics, Corrosion Resistance and Bioactivity
Effects of Forming Voltage on Surface Characteristics and Shear Strength of Anodized Titanium
Electric Field-mediated Growth of Osteoblast on 3D Printed Ti-6Al-4V Alloy Porous Scaffolds under Dynamic Condition
Electrochemical Laboratory Biofilm Reactor and Its Validity
Electrophoretic Deposition of Functionalized Graphene on Ti6Al4V Alloy for Biomedical Applications
Electrospun Biomedical Nanotechnologies
Evaluating Mechanisms of Metastasis of Cancer Using a 3D Bone-mimetic Model
Fabrication of Zinc Doped Magnesium Silicate Ceramics for Orthopaedic Applications
Hierarchical Carbon Scaffolds for Tissue Regeneration: Case Study with Muscle Cell Development
High Temperature Anodization of Magnesium Based Alloys for Controlling Degradation in Physiological Environment
II Biological Window All-optical Imaging Players: A General Prospective and a Multifunctional Newcomer
Improving the Flexural Mechanical Properties of Bioactive Glass (13-93) Scaffolds for Structural Bone Repair
In Vitro Depth-dependent Hyperthermia of Human Mammary Gland Adenocarcinoma
In Vivo Evaluation of Novel Amorphous Silicon Oxynitrophosphide Implant Coatings for Rapid Bone Healing
Investigation of Corrosion-assisted Cracking of Magnesium Alloys under Appropriate Mechano-Chemical Conditions for Bio-implant Applications
Nanoscale Structure and Modification of Biomaterials
Nanoscale Surface Modification of Metallic Biomaterials for Orthopedic Applications
Nanostructured Amorphous Magnesium Phosphate/Poly (Lactic Acid) Composite Coating for Enhanced Corrosion Resistance and Bioactivity of Biodegradable AZ31 Magnesium Alloy
Novel Bioactive Glass Containing Dental Composites for Slowing Secondary Caries
On Additive Manufacturing and Restoration of Tooth Cavities Using Chemically Bonded Ceramics - an Overview
Osteoblast Functions in Functionally Graded Ti-6Al-4V 3D Printed Mesh Structures
Physically Crosslinked Injectable Composites for Bone Tissue Engineering
Preparation and Characterizations of Nano Composites Based on Biphasic Mixture of Bioactive Ceramics for Biomedical Applications
Processing and Characterization of Silicon Nitride Bioceramics
Silicon Nitride Implants with Complex Structures Created by Robocasting
Surface Texture and Wettability of Amorphous Metallic Biomaterials
Tantalum Diffusion Coating for Increasing the Biocompatibility of Conventional Metal Implant Alloys
The Synergy of Conventional Ceramic Forming and Electronic Device Manufacturing Process to Develop Hermetic High Density Feedthroughs for Miniature Implantable Medical Devices

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