|About this Abstract
||2017 TMS Annual Meeting & Exhibition
||Pan American Materials Congress: Advanced Biomaterials
||PAN-5: Injectable Bone Substitute of Fibroin and Nanohydroxyapatite
||Maritza Buitrago, Claudia Ossa
|On-Site Speaker (Planned)
Hydroxyapatite (HA) is the most similar calcium phosphate to mineral component of bones and hard tissues of the body, and the fibroin (SF) is a recent natural biomaterial obtained of the silk of the insects like the silkworms. In this work, HA nanorods were synthesized using precipitation reaction and hydrothermal treatment. HA powder obtained was characterized with DRX and TEM; SF was extracted of the cocoons of Bombyx Mori silkworm using separation and dilution methods. The obtained solution was characterized with FTIR and protein quantification. The injectable bone substitutes were fabricated with different relations of the components HA, SF and glutaraldehyde as crosslinker. The properties evaluated were: injectability using universal testing machine, and degradation in SBF during 21 days. The results show that the bone substitutes can be injectable manually. Also, degradation results were positive because the material did not modify the medium considerably.
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