|About this Abstract
||2017 TMS Annual Meeting & Exhibition
||Recent Developments in Biological, Structural and Functional Thin Films and Coatings
||Osteoanabolic Implant Materials for Orthopaedic Treatment
||Xiaobo Chen, Yun-Fei Ding, Rachel Li, M. Nakai, M. Niinomi, Paul N Smith, Nick Birbilis
|On-Site Speaker (Planned)
Osteoporotic bone is more prone to fracture than normal bone, and current orthopaedic implant materials are not ideal for the osteoporotic cases. A newly developed strontium phosphate (SrPO4) coating is reported herein, as applied to Ti-29Nb-13Ta-4.6Zr (wt.%), TNTZ, an implant material with a comparative Young’s modulus to that of natural bone. TNTZ with excellent biocompatibility and high bio-inertness was pretreated in a concentrated alkaline solution under hydrothermal conditions, followed by a hydrothermal coating growth process to achieve complete SrPO4 surface coverage with high bonding strength. Owing to the release of Sr ions from the SrPO4 coating and its unique surface topography, osteoblast cells demonstrated increased proliferation and differentiation, whilst the cellular responses of osteoclasts were suppressed, compared to the control case, i.e. bare TNTZ.
||Planned: Supplemental Proceedings volume