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Meeting 2018 TMS Annual Meeting & Exhibition
Symposium Biodegradable Materials for Medical Applications
Presentation Title Biological Response of Surface Modified Mg-Sr Alloy for Orthopedic Applications
Author(s) Krishna Chaitanya Nune, Devesh Misra, Lili Tan, Weidan Wang, Xiaoming Yu, Ke Yang
On-Site Speaker (Planned) Krishna Chaitanya Nune
Abstract Scope Magnesium alloys are being widely used as biodegradable metals in orthopedic applications because of their unique properties such as low density, high specific strength, and good recyclability. However, the rapid degradation behavior is a major concern for its application as a load bearing implant. In this regard, we modified the surface of a Mg-1.5Sr alloy with micro-arc oxidation and Sr-P and Ca-P coating deposition to tune the biodegradation behavior and cellular response. The surface modified Mg-1.5Sr alloy has shown controlled degradation and no cytotoxicity, in comparison to bare Mg-1.5Sr alloy. Degradation products were characterized using EDS and FTIR spectrum, confirming the presence of apatite and magnesium oxide, with higher content on bare Mg-1.5Sr alloy. Sr-P coating has shown higher expression of proteins, stronger cell adhesion and high degree of proliferation and mineralization potential in comparison to other samples. Furthermore, no cytotoxicity was observed on the studied samples.
Proceedings Inclusion? Planned: Supplemental Proceedings volume

OTHER PAPERS PLANNED FOR THIS SYMPOSIUM

Biocompatibility of Biodegradable Mg-Zn-Ca Metallic Glass
Biodegradable Borate Glass for Wound Healing and Bone Regeneration Implants via Boronizing
Biodegradable Mg-implants – Current Market Experiences
Biological Response of Surface Modified Mg-Sr Alloy for Orthopedic Applications
Comparative Study on Corrosion Behavior WE33 in Immersion and Polarization Influenced by Heat Treatment
Corrosion Properties of Mg-Ca-Gd Alloy Applied to Biodegradable Implants
Designing Polymeric Membranes for Medical Applications
Development of a Bioresorbable Vascular Scaffold for Treating Coronary Artery Disease: A Case Study
Development of a New Biodegradable Surgical Clip Made of a Magnesium Alloy: Evaluation of its Safety and Tolerability for Canine Cholecystectomy
Development of Biodegradable Operative Zinc Clips for Ligation
Development of Porous and Biodegradable Hydroxyapatite/Mg Alloy Composite as Biodegradable Implants for Orthopaedic Applications
Effect of Additive Zinc on Mechanical Properties and Degradation Behavior of Magnesium
Fe-based Alloys: A New Class of High Strength Low-degradation Biodegradable Metals for Health Applications
Fundamentals of the Theory of Biodegradable Metals—Definition, Biodegradability and Biosafety Criteria and its Guidance on Material Design
Influence of Casting on Microstructure and Corrosion of Mg-Ca-Zn Alloys for Biomedical Application
Is Corrosion Fatique Relevant for Biodegradable Magnesium Implants?
Long Term Biocompatibility of Zinc and its Alloys for Absorbable Vascular Scaffolds
Mechanical and Corrosion Property Profile of Biodegradable, Open-porous Scaffolds Made of Sintered Magnesium Short Fibers
Mechanical Properties of Nanocrystalline Bioresorbable Fe-Mn Alloy
Metal Injection Molding (MIM) of Mg-alloys for Biomedical Applications
Microstructural Evolution and Mechanical Properties of Zn-Ti alloys for Biodegradable Stent Applications
Microstructure and Mechanical Properties of Mg-Gd Alloys as Biodegradable Implant Materials
Microstructure Properties and In-vitro Degradation Behavior of the Bioresorbable Magnesium Alloy ZNdK100
Opportunities Offered by Zinc Alloys for Degradable Implants: Recent Trends and Developments
Osteosynthesis in a Growing Ovine Model using Bioresorbable Rare-earth-free Magnesium Screws
Osteosynthesis in an Osteoporotic Rat Model Using Magnesium-based Pins
Progress in Absorbable Wire Technology for Next Generation Devices
Resoloy – the Resorbable Mg Alloy for Stents
Study of Biodegradable Zn-Cu-based Alloys for Cardiovascular Stents Applications
Study on Polylactide-coconut Fibre for Biomedical Applications
Surface Modification of Biomaterials by Plasma-based Technology
The Preparation of a Mg-Zn-Nd Alloy Wire and its Potential Application in Medicine
Visualisation of Implant Failure by Synchrotron Tomography
Where Do We Stand on Development of Ideal Biodegradable Zinc Material for Vascular Stenting?

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