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Meeting 2018 TMS Annual Meeting & Exhibition
Symposium Bio-nano Interfaces and Engineering Applications Symposium
Presentation Title Single Molecular Imaging of Fluorescent-tagged Peptides Diffusing on a Surface of Boron Nitride
Author(s) Peiying Li, Takakazu Seki, Linhao Sun, Yuhei Hayamizu
On-Site Speaker (Planned) Yuhei Hayamizu
Abstract Scope Specific peptides can spontaneously organize on a solid surface. Functionalization of surfaces of inorganic materials with these peptides is essential for biological applications, such as biosensor, drag delivery. Recently, engineered peptides on two-dimensional materials have demonstrated a spontaneous organization into long-range ordered nanostructures with six-fold symmetry. During the process of self-organization, there are three steps: (1) binding, (2) diffusion, and (3) ordering.1 It is important to investigate these processes individually for the control of the self-organization. While the ordering of peptides has been studied, the diffusion process is not fully understood, due to technical difficulties in the atomic force microscopy. In the kinetics of peptide self-organization, the diffusion process is needed to be studied more systematically. We utilized a high-sensitive fluorescent microscopy with fluorescent tagged peptides for a single molecular imaging to quantitatively investigate the diffusion process. In the presentation, we will discuss quantitative physical parameters in the diffusion process.
Proceedings Inclusion? Planned: Publication Outside of TMS (Indicate publication title and publisher if known.)

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Bioconjugated Nanoparticle Imaging Probes for Molecular Imaging with Computed Tomography
Biofilm Formation Behavior on Polymer Brush Surfaces by E.coli and S. Epidermidis
Biomolecular Design of Soft Interfaces for Technology and Medicine
Chemically Functionalised Graphene FET with Double Conductance Minima for the Label-free Sensing of Exosomes
Computational Study of Selective Adsorption of Peptides on MoS2 Surface
Connecting Biology and Electronics with Protons: From Ion Channels to Cells
Discovery of Biomaterials by Simulation and Experiment: Catalysts, Composites, and Therapeutics
Effects of Hydration and Mineralization on the Mechanical Behavior of Collagen Fibrils
Investigating the Interaction of Amyloidogenic Proteins with Inorganic Surfaces, Nanoparticles and Biomolecules by Atomistic Simulations
Modeling the Mechanics of Cancer Cells on Tissue Engineering Substrates
Nanoclay Based Tissue Engineering Scaffolds for Mimicking Biointerfaces in Mesenchymal to Epithelial Transision of Prostate and Breast Cancer Metastasis to Bone
Nanoscale Structure and Properties of Biomaterials
New Antimicrobial Peptides Generated through Genetic Algorithm Approach Using Chemical Property Based Cross-over
Oligopeptides and Recombinamers at Surfaces and Interfaces to Address Oral Infections
Revealing the Full Hierarchical Structure of Spider Silks across All Length Scales
Revealing the Multi-functional Surface and Material Property of Venus Flytrap (Dionaea Muscipula)
Single Molecular Imaging of Fluorescent-tagged Peptides Diffusing on a Surface of Boron Nitride
Smart Biomaterials for MoS2 and Gold Mining
Surface Modification of Ti6Al4V to Confer Antibacterial Properties against Listeria Monocytogenes
Synthesis and Characterization of Superomniphobic Surfaces Inspired by Springtails
Transmission Synchrotron X-ray Tomography and Nano-indentation Measurements for the Investigation of the Teeth Microstructure of Dinosaurs
Use of Nanostructured Diamond in Medical Device Applications

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