About this Abstract |
Meeting |
MS&T22: Materials Science & Technology
|
Symposium
|
Advances in Surface Engineering
|
Presentation Title |
Irreversible Bonding of Polymer-based Microfluidic Systems to Support Biological Experiments on the International Space Station (ISS) |
Author(s) |
Annaliza Perez-Torres, Paul Kuehl, Shelby Giza, Molly Sullivan |
On-Site Speaker (Planned) |
Annaliza Perez-Torres |
Abstract Scope |
Polymers are appealing substrate materials for microfluidic systems, including various benefits in developing low-mass and low-cost reusable devices to support biological experiments in the International Space Station (ISS). While much research focuses on the rapid manufacturing of thermoplastic microfluidic components, sealing these microfluidic devices to create enclosed microchannels allows biological experiments to function on the ISS. In this study, we use mechanical etching and chemical treatments such as aminopropyltriethoxysilane (APTES) and 3-glycidoxypropyltrimethoxysilane (GLYMO) to treat the surfaces of the Polyether ether ketone (PEEK) and Polydimethylsiloxane (PDMS). The microfluidic structures are bonded using biocompatible thermal and UV curable glues, which can hold pressures up to 21 psi. The changes in surface properties will be characterized using different techniques, and we validate the biocompatibility of the bonded materials according to ISO 10993. |