|About this Abstract
||Materials Science & Technology 2011
||Next Generation Biomaterials
||Synthesis and Properties of Nano-Calcium Phosphates for Biomedical Applications
||Darcy Wagner, Huan Zhou, Joseph G Lawrence, Sarit B Bhaduri
|On-Site Speaker (Planned)
Calcium phosphate (CaP) materials are widely used in medical applications, but their biological interactions are primarily determined by their nanoscale properties. The majority of the conventional synthesis methods for CaP yield large grain sizes which are associated with poor mechanical properties. Therefore, these materials have had limited applicability. Advancements in synthesis methods for nano-CaP have broadened their potential applications. While a variety of heat treatment methods exist, microwave sintering of nano-CaP produces materials with smaller grain sizes and produces a material with enhanced mechanical properties. The thermal profile generated via bulk microwave heating increases porosity and total surface area. Increased porosity is associated with increased cellular adhesion and proliferation, both of which are critical for tissue engineering applications. Increases in surface area are known to be beneficial for drug and gene therapies. Calcium phosphates are especially promising in orthopedics owing to their similarity with mammalian bone.