|About this Abstract
||2018 TMS Annual Meeting & Exhibition
||Biological Materials Science
||Reduction of Osteoporosis by Means of Hydrogels and Nanohydroxyapatite with Integration of Magnesium
||Gerardo Presbitero, Laura Peña , Cristina Piña, M. A. L. Hernandez-Rodríguez
|On-Site Speaker (Planned)
The number of hip fractures due to osteoporosis in Mexican men and women will increase to 226,886 cases by 2050, and worldwide could reach until 6.3 million. Additionally, magnesium deficiency in bone results in development of osteoporosis and its use in the development of biomaterials has great contribution towards the regeneration of tissues. Due to these reasons, it is being developed sodium alginate and chitosan hydrogels reinforced with nanohydroxyapatite, with integration of magnesium to facilitate the acceleration of remodelling. It is combined chitosan with hydroxyapatite nanoparticles to increase the mechanical properties, and from each hydrogel it is obtained several samples with different percentages of elements to measure their variation of properties. It is acquired good consistency and durability of the hydrogel. Such scaffolds provide the support and filling required for the tissue affected by osteoporosis, while magnesium will allow regeneration until the physiological properties of the tissue have been recovered.
||Planned: Supplemental Proceedings volume