|About this Abstract
||2018 TMS Annual Meeting & Exhibition
||Biodegradable Materials for Medical Applications
||Visualisation of Implant Failure by Synchrotron Tomography
||Regine Willumeit-Roemer, Julian Moosmann, Berit Zeller-Plumhoff, Florian D.C. Wieland, Diana Krüger, Björn Wiese, Ann Wennerberg, Niccolò Peruzzi, Silvia Galli, Felix Beckmann, Jörg U. Hammel
|On-Site Speaker (Planned)
Magnesium (Mg) and its alloys degrade under physiological conditions. But how strong is the connection between the implant, the corrosion layer and the surrounding tissue, namely bone? Biomechanical tests like push-out tests have shown that a degraded Mg-pin is surprisingly well connected (Castellani et al. Acta Biomat 7 (2011) 432–440) with the bone. With high-resolution synchrotron tomography and small angle X-ray scattering a deep look into the microstructure of the material as well as the bone during deformation until fracture is possible. Strain fields can be calculated which are correlated with multimodal data to provide deep insight into the impact of the degradation process of the screw on the process of the bone remodeling revealing information on how Mg implants are incorporated and which factors contribute to a tight junction.
||Planned: Supplemental Proceedings volume