Semisolid processing can be advantageously used in multiphase high-entropy alloys (HEAs) to produce components with complex geometries. In association with 3d transition metals, Cu can lead to phase separation and formation of phases with lower melting temperatures, which can be conveniently explored in semisolid technology. Accordingly, this study aimed to analyze the effect of Cu content on the melting behavior, phase formation, and semisolid microstructural evolution of CrCuFeMnNi alloys. The melting process was evaluated by DSC, whereas microstructural characterization involved SEM and XRD investigations. The melting spectrum revealed three peaks related to the main phases in the microstructure. As expected, the Cu-rich phase had the lowest melting temperature, allowing the partial melting experiments to be carried out at 1080 °C. The liquid fraction increased with Cu content, while fine and globular solid phases were obtained. Therefore, it is suggested that CrCuFeMnNi alloys can be properly processed in the semisolid state.