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Meeting 2016 TMS Annual Meeting & Exhibition
Symposium Magnesium-based Biodegradable Implants
Presentation Title Degradation of MgF2-coated and Uncoated MgNd2 Specimens in Contact with Nasal Mucosa
Author(s) Rainer Eifler, Martin Durisin, Christian Klose, Thomas Lenarz, Hans Jürgen Maier
On-Site Speaker (Planned) Rainer Eifler
Abstract Scope The magnesium-neodymium alloy MgNd2 offers an elongation of 30%. Therefore, it is well suited as a material for resorbable stents which can be used for treating chronic sinusitis. While the alloy’s corrosion properties were already investigated in vitro, the present study focuses on the in vivo degradation behavior of fluoride-coated and uncoated specimens in direct contact with porcine nasal mucosa during a period of 180 days. The study showed a promising and controlled biodegradation, which was investigated by measurements of the MgNd2 specimens’ mass and volume losses as well as element analyses on the surface to obtain information about the composition of the degradation layer. The degradation rates of the uncoated samples in direct contact with the physiological tissue showed a maximum during the first 45 days which then decreased for the remaining implantation period. In contrast, the degradation rates of the fluoride-coated samples increased gradually during the implantation duration.
Proceedings Inclusion? Planned: A combination print-CD volume

OTHER PAPERS PLANNED FOR THIS SYMPOSIUM

Absorbable Filament Technologies: Wire-drawing to Enable Next-generation Medical Devices
Appropriate Corrosion-FatigueTesting of Magnesium Alloys for Temporary Bio-implant Applications
Computer Simulation of the Mechanical Behaviour of Implanted Biodegradable Stents in a Remodelling Artery
Degradation of MgF2-coated and Uncoated MgNd2 Specimens in Contact with Nasal Mucosa
Fabrication, Testing and Performance of Rare Earth-containing Magnesium Biodegradable Metals
In Vitro Corrosion and Cytocompatibility Properties of Mg-2Gd-X(Ag, Ca) Alloys
Influence of Precipitation Hardening in Mg-Y-Nd on Mechanical and Corrosion Properties
Magnesium-based Compression Screws
Magnesium Powder Injection Molding (MIM) of Orthopedic Implants for Biomedical Applications
Manufacturing of Osteosynthesis Systems Made of Magnesium Alloy AZ91
Monitoring Biodegradation of Magnesium Implants with Sensors
Plasma Surface Modification of Magnesium-Based and Related Biomaterials
Standardized Guidance for the Preclinical Evaluation of Absorbable Metal Implants
The Industrial Challenges of Manufacturing Bioabsorbable Magnesium
Understanding Corrosion-assisted Cracking of Magnesium Alloys for Bioimplant Applications

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