|About this Abstract
||2016 TMS Annual Meeting & Exhibition
||Magnesium-based Biodegradable Implants
||Degradation of MgF2-coated and Uncoated MgNd2 Specimens in Contact with Nasal Mucosa
||Rainer Eifler, Martin Durisin, Christian Klose, Thomas Lenarz, Hans Jürgen Maier
|On-Site Speaker (Planned)
The magnesium-neodymium alloy MgNd2 offers an elongation of 30%. Therefore, it is well suited as a material for resorbable stents which can be used for treating chronic sinusitis. While the alloy’s corrosion properties were already investigated in vitro, the present study focuses on the in vivo degradation behavior of fluoride-coated and uncoated specimens in direct contact with porcine nasal mucosa during a period of 180 days. The study showed a promising and controlled biodegradation, which was investigated by measurements of the MgNd2 specimens’ mass and volume losses as well as element analyses on the surface to obtain information about the composition of the degradation layer. The degradation rates of the uncoated samples in direct contact with the physiological tissue showed a maximum during the first 45 days which then decreased for the remaining implantation period. In contrast, the degradation rates of the fluoride-coated samples increased gradually during the implantation duration.
||Planned: A combination print-CD volume