|About this Abstract
||2017 TMS Annual Meeting & Exhibition
||Biological Materials Science
||H-27: Porous 45S5 Bioglass®-based Scaffolds Using Stereolithography: Effect of Partial Pre-sintering on Structural and Mechanical Properties of Scaffolds
||Boonlom Thavornyutikarn, Terence Turney, Passakorn Tesavibul, Kriskrai Sitthiiseripratip, Nattapon Chatarapanich, Bryce Frltis
|On-Site Speaker (Planned)
Scaffolds made from 45S5-Bioglass (BG) show clinical potential in bone regeneration due to their excellent bioactivity and ability to bond to natural bone tissue. However, porous BG scaffolds are limited by their mechanical integrity and by the substantial volume contractions occurring upon sintering. This study examines stereolithographic (SLA) methods to fabricate mechanically robust and porous Bioglass-based scaffolds, with regular and interconnected pore networks and with various computer-aided design architectures. It was found that a diamond-like (DM) architecture gave scaffolds the most controllable results without any observable closed porosity in the final scaffolds. When the pore dimensions of the DM scaffolds of the same porosity (~60 vol%) were decreased from 700 to 400 μm, the compressive strength increased from 3.5 to 6.7 MPa. Additionally, smaller dimensional shrinkage could be obtained by employing partially pre-sintered bioglass, compared to standard 45S5 Bioglass. Scaffolds derived from pre-sintered bioglass also showed marginally improved compressive strengths.
||Planned: Supplemental Proceedings volume