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Meeting Materials Science & Technology 2011
Symposium Next Generation Biomaterials
Presentation Title Influence of Scaffold Hydration on Fiber Geometry and Extension
Author(s) Greg Ebersole, Jackie Ohmura, Peter M Anderson, Heather M Powell
On-Site Speaker (Planned) Heather M Powell
Abstract Scope Electrospun tissue engineering scaffolds are hydrated prior to use; however, their fiber properties are most commonly quantified using non-hydrated scaffolds. This work explores how the hydration state of electrospun scaffolds affects fiber geometry and extensional response. In particular, scanning electron microscopy was used to record the x-y coordinates for individual fibers within two types of dry scaffolds: collagen and polycaprolactone (PCL). Confocal microscopy was used to provide similar data for wet counterparts. The results show that fiber tortuosity increases substantially with hydration for collagen and less so for PCL. These differences in fiber tortuosity are captured in terms of Fourier signatures, which can be used to construct statistical variations of fiber shape. Finite element analysis of single fibers documents how the increased tortuosity in wet collagen fibers affects extensional response. The results show that hydrated geometries are required to properly capture fiber shape and its effect on mechanical response.
Proceedings Inclusion? Undecided


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Alkoxysilane Mediated Generation of Gold Nanoparticles: Development of Novel Electrocatalytic Materials
An Experiment-Simulation Approach to Determine Electrospun Fiber Properties
Angiogenic Bioactive Borate Glasses
Application of Polymer-Based Microfluidic Devices for the Selection and Manipulation of Low-Abundant Biological Cells
Bio-Doped Metal Oxides for High-Throughput Biosensors
Bioactive Glass in Tissue Engineering
Biodegradable Polymer-Hydroxyapatite Composite Scaffolds: Fabrication and Properties
Biological Aspects of Chemically Bonded Ca-Aluminate Based Biomaterials
Biologically Inspired Origami (BIO) Paper for Tissue Engineering Scaffolds
Biomaterials: From Models to Spectroscopic Characterization
Biomedical Titanium Alloy with Ultralow Elastic Modulus and High Strength
BioMEMS Devices and Applications of Parylene Biocompatible Coating
Collagen-Hydroxyapatite Mechanics in Human Bone
Comparison of Microstructures and Mechanical Properties for CoCrMo Biomedical Implant Prototypes Fabricated by EBM and Failed Implants by Traditional Manufacturing
Corrosion Behaviour of Ti-Base Alloys in Biocompatible Solutions
Corrosion Resistance and Cytotoxicity of Degradable Metallic Implants for Orthopedic Applications
Degradation of Tailored Amorphous Multi Porous (TAMP) Bioscaffolds
Deposition & Characterization of Electrochemically Induced Hydroxy-Apatite Coating
Development of Magnesium-Zinc-Calcium Biodegradable Alloys
Diode Laser Surface Treated Commercially Pure Titanium: Corrosion and Wear Investigation
Directed Bone Regeneration to Prevent Fatigue Failure of Osteoceramic Orthopedic Implants
Effect of Heat Treatment and Boron Content on the Behavior of Ti Alloys in PBS and 0.9 wt% NaCl Solutions
Electrically Triggered Drug Delivery Using Nanoporous Electrodes
Electrochemical Characterization of the Eastern Oyster Crassostrea Virginica Shell as a Bioceramic Material
Electrochemically Controlled Switching Properties in Bioinspired Polymer Nanocomposites
Enhancement of Apatite Formation by Oxynitridation of Ti Substrate
Fabrication Approaches and Characterization of Porous 3D Bioscaffolds for Hard Tissue Augmentation
Fatigue Behavior of Open-Cellular Ti-6Al-4V Biomedical Prototypes Fabricated by Electron Beam Melting
Fatigue Life of Hydroxyapatite Whisker Reinforced Polyaryletherketones
Human Fetal Liver Cell Culturing in Porous Hydroxyapatite/Hyaluronic Acid Composites
Hybrid Biomaterials
Hydrolysis of Monetite/Chitosan Composites in Alpha-MEM & SBF Solutions
In-Vitro and In-Vivo Osteocompatibility Assessment for Carbon Nanotube Reinforced Hydroxyapatite Coatings
In-Vivo Evaluation of 13-93 Bioactive Glass Scaffolds Made by Selective Laser Sintering (SLS)
In Situ Mineralization of Hydroxyapatite in Intercalated Nanoclays for Bone Tissue Engineering
Influence of Scaffold Hydration on Fiber Geometry and Extension
Injectable Bone Mineral Cements: Current and Future Trends
Iron/Iron Oxide Core/Shell Nanoparticles for Magnetic Hyperthermia Treatment
Laser Processed Tantalum: Mechanical, In vitro Wear and Biological Properties
Local Drug Delivery Techniques for the Prevention of Implant-Associated Infections
Low Temperature Sintering of Ti-6Al-4V for Orthopedic Implant Applications
Magnesium-Titanium Alloys for Biodegradable Implants
Materials Development for Biomimetic Engineered Skin Mechanics
Mechanical and Microstructural Characterization of 45S5 Bioglass® Scaffolds for Tissue Engineering
Multi-Scale Porosity in Artificial Bone Scaffolds by Robocasting
Multi-Signal FIB/SEM Tomography of Bone on Dental Implants
Nanoscale Modification of Biomaterials to Control Cell Growth
Next-Generation Rotary Endodontic Instruments Fabricated from Special NiTi Alloy
Next Generation Orthopaedic Implants by Additive Manufacturing Using Electron Beam Melting
Origins of the Fracture Resistance of Bone and Its Biological Degradation
PCL-Gelatin Nanofibers for Extended Drug Release
PLGA Nanoparticles: A Versatile Platform for Drug Delivery
Porosity Dependent Strength and Elastic Modulus of Hydroxyapatite and Other Oxide and Non-Oxide Materials
Post-Electrospinning Modification of Chitosan Fibers
Predicting Microstructure Evolution in Drug Eluting Coatings
Preparation and Characterization of Nanophase Hydroxyapatite via Self-Propagating High Temperature Synthesis and Aqueous Precipitation
Preparing PLA Powders for Powder-Based Processing Using a Solvent-Non-Solvent Mediated Technique
Probing Molecular Polarization at Interfaces of De Novo Proteins and Electrode Surfaces
Processing Effects on the Crystallinity, Microstructure, and Mechanical Properties of Hydroxyapatite Reinforced Polyetheretherketone Scaffolds
Resorbable Calcium Phosphate Scaffolds in Bone Tissue Engineering
Scaffolds to Guide Stem Cells for Bone and Dentin Regeneration
Stability of Boron-Containing Titanium Alloys in Saline and Related Bioreceptor Studies
Surface Engineering Approaches for Beta Titanium Alloys Used in Orthopedic Implants (Invited)
Synthesis and Characterization of Gel Casting and Freeze Casting Derived Porous Bioceramic Scaffolds
Synthesis and Properties of Nano-Calcium Phosphates for Biomedical Applications
The Effects of Sn Addition on Mechanical Behavior of Ti-24Nb-4Zr-3Mo (8-12) Sn Alloys
Third Body Challenges in Total Hip Arthroplasty
Titanium with Designed Elongated Pores for Biomedical Implants
Use of Pore Structure to Manipulate the High Temperature Decomposition of Hydroxyapatite
Young’s Modulus Changeable Biomedical Titanium Alloy for Preventing Stress Shielding and Spring-Back

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