|About this Abstract
||Materials Science & Technology 2012
||Nanotechnology for Energy, Environment, Healthcare and Industry
||Phase Field Modeling of Electrochemical Transport in Nanoparticles for Medical Applications
||Jon Guyer, David Saylor, James Warren
|On-Site Speaker (Planned)
Nano-particulate silver systems are widely used in wound dressings, surgical masks, and catheter coatings as anti-microbial agents. We have shown that a phase field model of the electrochemical interface captures behaviors including electrocapillary phenomena, differential capacitance curves that resemble experimental measurements, and non-linear kinetics consistent with the empirical Butler-Volmer relation. Although numerical constraints limit the applicability of this model to dimensions of a few nanometers, the model is capable of making predictions at precisely the spatial and temporal scale that we are interested in for studying medical applications of silver nano-particles. We will discuss the impact of particle size, solution concentration, and particle aggregation on ion release and surface charge, which not only impact the anti-microbial efficacy and system stability, but may also affect biocompatibility. Finally, we will discuss our efforts to extend the length and time scales of the model.