The Off-Gas Sigma Team was formed in late fiscal year 2009 to integrate and coordinate the Fuel Cycle Research and Development activities directed toward the capture and sequestration of the volatile and semivolatile radionuclides from fuel reprocessing. The four primary volatile radionuclides of interest are iodine-129, carbon-14, krypton-85, and tritium. The Sigma Team concept was envisioned to bring together multidisciplinary teams from across the US Department of Energy complex that would work collaboratively to solve the technical challenges and develop the scientific basis for the capture and immobilization technologies such that the sum of the efforts was greater than the individual parts. The laboratories currently participating in this effort are Argonne National Laboratory, Idaho National Laboratory, Oak Ridge National Laboratory, Pacific Northwest National Laboratory, and Sandia National Laboratories. This paper highlights a number of the significant accomplishments of the Off-Gas Sigma Team.