Twin roll casting (TRC) process is the most cost competitive casting process to produce wrought Mg alloys. As TRC process involves both casting and rolling of thin strip, there is a certain limitation for the choice of Mg alloys to be produced via this process. At the moment, this process is successfully applied to the production of limited AZ series Mg alloys with low Al content. There has been great interest in the development of new wrought Mg alloys suitable for TRC process for automotive applications. In this presentation, the TRC process will be firstly reviewed, and the TRC Mg alloy design concept will be presented. In particular, the current gap of the ICME approach for the development of new Mg alloy suitable for the TRC process will be discussed.