|About this Abstract
||2017 TMS Annual Meeting & Exhibition
||Advanced Materials in Dental and Orthopedic Applications
||Functionalization of Dental Titanium Implants for Improved Osteointegration
||Genevieve Pourroy, Fabienne Perrin-Schmitt, Van Quang Le, Mathilde Giraudel, Caroline Fischer, GÚraldine Koenig, Leandro Jacomine, Luc Behr, Alain Chalom, Laurence Fiette, Alexis Morlet, Adele Carrad˛
|On-Site Speaker (Planned)
This study aims to improve the strength and quality of the titanium (Ti)-hydroxyapatite (HA) interface to prevent long-term failure of the implanted devices originating from coating delamination and to test it in an in-vivo model. Thermochemical treatments of the acid-etched dental commercial Ti implants were combined with sol-gel HA coating processes to obtain a nanoporous hydroxyapatite/sodium titanate bilayer. The in vitro results on murine MC3T3-E1 and human SaOs-2 cells confirm the advantage of this coating regarding the capacity of cell growth and differentiation. Functional and histopathological evaluations of the coated Ti implants were performed at 22, 34 and 60 days of implantation in a dog lower mandible model. Osteoconduction and osteointegration mean scores were higher for test implants compared to the controls at 22 and 34 days.
||Planned: Supplemental Proceedings volume