|About this Abstract
||2017 TMS Annual Meeting & Exhibition
||Biological Materials Science
||Osteoporosis and Fatigue Fracture Prevention by Analysis of Bone Microdamage
||Gerardo Presbitero, David Gutierrez, David Taylor
|On-Site Speaker (Planned)
It is analyzed the conditions in which microcracks generated by fatigue interfiere to the fracture of bones, orienting towards the prevention of fractures of bones with osteoporosis. Mechanical tests, statistic analyzes and the development of a novel theoretical model were employed to describe the way microcracks grow towards the generation of bone fractures, basing on a concept named characteristic length. Bone mineral density and effects caused by gamma radiation for sterilization purposes of human bones used as allografts, contribute to the description of microcracks generation and growth to cause the fracture of bones. The bones weakened in their mechanical properties will fracture by fatigue in vivo conditions according to the manner in which characteristic lengths increase. The presented results will allow the development of predictions towards the prevention of fatigue fractures of bones of elderly people with osteoporosis, and will be useful for the development of new clinical approaches.
||Planned: Supplemental Proceedings volume