|About this Abstract
||Materials Science & Technology 2012
||Surface Properties of Biomaterials III
||Dependency of Cell Attachment and Proliferation on the Surface Roughness of HA and Ti-6Al-4V
||Ling Li, Kyle Crosby, Monica Sawicki, Leon Shaw, Yong Wang
|On-Site Speaker (Planned)
Functionally graded Ti-6Al-4V (Ti)/hydroxyapatite (HA) implant materials with a Ti-core and HA-rich surface have the potential to offer orthopedic implants with good strength and an osteoconductive surface. In this study, we have investigated the effect of surface roughness of HA and Ti on cell attachment and cell proliferation. The samples are prepared via sintering and polished with SiC papers, resulting in different surface roughness grades. Cell attachment and proliferation properties are investigated following various incubation periods. We find that cell attachment and proliferation of ROS 17/2.8 cells increase as the roughness of HA and Ti is increased. This behavior is explained by selective adsorption of serum proteins.
||Planned: None Selected