The virtues of altering microstructures via Severe Plastic Deformation (SPD) have been explored in virtually every commercial alloy system. However, the processing of these alloys via industrial scale implementations of SPD remains limited. In order to systematically evolve production of ultrafine grain and nanostructured metals by SPD, a Nanostructured Metals Manufacturing Testbed (NMMT) has been established in Golden, Colorado. Machines for research scale and pilot scale implementation of Equal Channel Angular Pressing-Conform (ECAP-C) technology are operated continuously in the NMMT to systematically assess the practical limitations of the SPD processing and evolve the foundational science and manufacturing technologies. We review highlights of ongoing work for scaling processing of aluminum, copper, magnesium, titanium, and iron-based alloys. Topics important to pilot scale processing include fundamental science to control slip, twinning, and texture evolution, plus industrial issues of tooling lifetimes, lubrication schemes, minimizing galling and adhesive wear, and tolerances for tooling.