A positive correlation between the grain boundary character distribution and enhancements in properties is now well-established. What is frequently ignored, however, is the role of the correlated grain boundary network or the long-range orientation neighborhood, with most studies focusing on the characteristics of the individual boundaries. In this context, the development of twin-related domains (TRD) that comprise a supra-grain network in the microstructure has been little studied, though one can readily recognize their importance for intergranular processes, say crack propagation. In this presentation, we will attempt to address this issue: first, we will show examples where TRDs matter, and second, follow, statistically, the evolution of the complex morphology of TRDs during recrystallization and grain growth processes. This work was performed under the auspices of the US Department of Energy by Lawrence Livermore National Laboratory under Contract DE-AC52-07NA27344, and supported by US DOE OBES, Materials Science and Engineering Division.