Recently legislated fuel economy standards require new U.S. passenger vehicles to achieve at least 58 MPG by 2030, up from 28.8 MPG today. Two major methods of achieving improved fuel economy in passenger vehicles are reducing the weight of the vehicle and developing high-performance engines. To reduce the weight of the vehicle advanced cast aluminum and magnesium alloys are being increasingly used in both automotive powertrain and body applications. To increase engine efficiency, the maximum operation temperature of these components has increased from approximately 170°C in earlier engines to peak temperatures well above 200°C in recent engines. The increase in the operational temperatures requires a material with optimized properties in terms of tensile, fatigue and thermos-mechanical fatigue strength. ICME models play an important role in accelerating the development of new alloys, design and optimization of the performance of the components. This talk will present two examples which demonstrate the recent development of ICME models at Ford for advanced cast aluminum and magnesium alloy applications, and identify the gaps in meeting the challenging requirements in ICME approach.