|About this Abstract
||2016 TMS Annual Meeting & Exhibition
||2016 Functional Nanomaterials: Emerging Nanomaterials and Techniques for 3D Architectures
||Simple Green Synthesis of Amino Acid Functionalised CdTe/CdSe/ZnSe Core-multi Shell with Improved Cell Viability for Cellular Imaging
||Vuyelwa Ncapayi, Oluwafemi Samuel Oluwatobi, Sandile P Songca, Tetsuya Kodama
|On-Site Speaker (Planned)
||Oluwafemi Samuel Oluwatobi
We herein report a simple, economical and green synthesis of highly fluorescent, water soluble and stable arginine functionalised CdTe/CdSe/ZnSe multi core-shell nanoparticles (NPs) for cellular imaging. The synthesis of the CdTe/CdSe/ZnSe NPs was carried out under ambient conditions in the absence of an inert environment and involved the use of K2TeO3 and Na2SeSO4 as a stable tellurium and selenium precursor respectively. The as-prepared NPs were characterised using UV-Vis absorption and photoluminescence (PL) spectroscopy, dynamic light scattering (DLS), Fourier transform infrared spectroscopy (FTIR), transmission electron microscopy (TEM), high resolution transmission electron microscopy (HRTEM). The optical analyses showed an enhancement in the fluorescent intensity after the functionlisation with improved quantum yield. The functionalised NPs (F-NPs) showed reduced cytotoxicity compared to the bare NPs when investigated on KM-Luc/GFP cell line at different concentrations. The fluorescent imaging performed using confocal fluorescent microscope indicated that the as-synthesised functionalised NPs were taken up by the cells.