A biomaterial can be defined as “a material intended to interface with biological systems to evaluate, treat, augment or replace any tissue, organ or function of the body” . Regarding recent materials developed for implant devices, such as Ti-6Al-4V, there still are a lack about toxicological effects for some of them.
Although extensively used, these alloys usually suffer tribocorrosion processes possibly releasing vanadium ions into the organism. In the literature, the action and damage dose of this element in live systems are not clear . Recent studies have demonstrated that vanadium causes cytotoxic effects and adverse tissue reactions . This contribution aims to review the actual knowledge of vanadium toxicity and its interaction with biological systems.
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