|About this Abstract
||2016 TMS Annual Meeting & Exhibition
||Bio Nano Interfaces and Engineering Applications
||An Electrochemical Approach to Control Surface Behavior of Peptides Self-assembling on Graphite
||Takakazu Seki, Christopher So, Tamon Page, Yuhei Hayamizu, Mehmet Sarikaya
|On-Site Speaker (Planned)
Aiming to construct nano-architectures of peptides on solid surfaces in a controlled manner, it is required to understand interactions between peptides and surfaces. Although electrostatic interaction is one of the most essential parameters during the surface process, the correlation between the nano-structures of peptides and surface potential has not been studied. In this work, we investigate the effect of the surface potential of graphite on the self-organization behavior of graphite-binding peptides (GrBP). Under the modulated surface potential, GrBPs form various ordered structures such as well-ordered nanowires, wavy wires, and islands. Systematic investigation reveals that the peptide sequence, especially the presence and also location of charged amino acids in the sequence, affects on not only surface coverage but also the morphological features of self-assembled peptides. Our results suggest that electrostatic interactions and local charge distribution in the electrochemical double layer is essential for the peptide self-assembly.
||Planned: Publication Outside of TMS (Indicate publication title and publisher if known.)