|About this Abstract
||2017 TMS Annual Meeting & Exhibition
||Biological Materials Science
||Wet-lay Textile Technique for Biological Fiber Reinforced Hydrogel Scaffolds
||Andrew Wood, Vinoy Thomas
|On-Site Speaker (Planned)
Chemical crosslinking forms strong inter-polymer bonds in hydrogels but typically uses reagents that are cytotoxic while physical crosslinking is more temperamental to environmental changes but can be formed without these toxic reagents. In this study, we added a biological fiber-reinforcement phase to a hydrogel, poly(vinyl alcohol), formed through successive freezing-thawing cycles by incorporating a non-woven soy-fiber mat formed by the wet-lay process. By reinforcing the hydrogel with a wet-laid fibrous mat, the mechanical properties have increased. The soy fibers were also found to be cytocompatible with endothelial cell viability showing around 96.51% after a 48 h. This novel approach to hydrogel-reinforcement presents a rapid, tunable method by which hydrogels can attain increased mechanical properties without sacrificing their inherent biologically favorable properties.
||Planned: Supplemental Proceedings volume