Copper sulfide minerals usually contain toxic minor elements such as As, Sb and Bi, which in Chilean concentrates are present mainly as stibnite Sb2S3, enargite Cu3AsS4, and bismuthinite Bi2S3. Current smelting processes cannot treat concentrates with high concentrations of these elements; therefore, they must be removed before smelting to avoid environmental pollution and a contaminated final copper product. Roasting is the classical process to eliminate arsenic by volatilization. However, antimony and bismuth do not volatilize efficiently in N2-O2 roasting at 500-700 °C. Hence, the chloridizing roasting of Sb2S3 using NaCl/CaCl2 was studied as alternative process to volatilize Sb. Results to date obtained in tube furnace and TGA systems in oxidizing atmosphere showed that Sb could be eliminated partially by chloridizing to about 50% with CaCl2. Increasing oxygen concentration had a negative effect forming nonvolatile SbO2 and Ca5Sb5O17 while the salt concentration and temperature affected little the Sb elimination.