|About this Abstract
||Materials Science & Technology 2012
||MS&T'12 Poster Session
||A2: Fabrication of Bio-Structures Via Microbubbling
||Zeynep Ekemen, Zeeshan Ahmad, Eleanor Stride, Mohan Edirisinghe
|On-Site Speaker (Planned)
Recent efforts in the biomaterials field have focused on developing polymeric materials for use in “smart” or multifunctional devices. One such area which has drawn considerable interest is microbubble fabrication. Although microbubbles are currently available for use as ultrasound contrast agents and drug delivery vehicles, their range of potential biomedical applications is much broader and encompasses templates for porous structures. The electrohydrodynamic microbubbling process, which is robust and extremely versatile, can be used to generate bubbles for such structures. In this work we demonstrate the generation of microbubbles coated with bovine serum albumin and silk with various concentrations and combination ratios. We show how the bubble size and size distribution can be controlled through parametric optimization and how the formed porous structures can be used as scaffold structures for biomedical applications using mouse cell lines. The processing methods can be readily applied to other biomacromolecules of significance in self-templating applications.
||Definite: A CD-only volume