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Meeting 2017 TMS Annual Meeting & Exhibition
Symposium Advanced Materials in Dental and Orthopedic Applications
Presentation Title Cellular Response of Escherichia Coli to Mg-2Zn-2Gd Alloy with Different Grain Structure: Mechanism of Disruption of Colonization
Author(s) Pramanshu Trivedi, K.C. Nune, R.D.K. Misra , A.K. Patel, K. Balani, R. Jayganthan
On-Site Speaker (Planned) Pramanshu Trivedi
Abstract Scope We describe here, the grain size dependent bactericidal effect of magnesium alloy. In this context, Mg-2Zn-2Gd alloy that was subjected to multiaxial forging (MAF) to obtain different grain size in the range of ~44 Ám to ~710 nm. Contact angle measurements using goniometer and wettability were assessed with water, SBF, n-Hexane and DMEM. The antimicrobial activity and the mechanism of inhibition of Escherichia coli (E. coli) bacterial cell attachment were determined as a function of grain size. The higher surface energy of ultrafine-grained Mg-2Zn-2Gd alloy led to the release of more Mg+2 ions at an early stage, which consequently increased the pH of fluid in the vicinity of the implant, therefore producing unfavorable environment for the survival of bacteria. This led to damage of bacterial cell walls and reducing their adhesion. Furthermore, a significant degree of apatite formation was indication of high bioactivity in the ultrafine-grained alloy.
Proceedings Inclusion? Planned: Supplemental Proceedings volume

OTHER PAPERS PLANNED FOR THIS SYMPOSIUM

A New Ni-free Beta-Ti Alloy with Large and Stable Room Temperature Super-elasticity
A Novel Strengthening Strategy Using Stacking Faults for Biomedical Co–Cr–Mo Alloys
Biodegradable Boron Coating for Wound Healing and Bone Regeneration Implants Via; DIMOX, Rheocasting and Thixocasting
Biomimetic Tooth Repair: Amelogenin-derived Peptides Enable In Vitro and In Vivo Enamel Remineralization
Cellular Response of Escherichia Coli to Mg-2Zn-2Gd Alloy with Different Grain Structure: Mechanism of Disruption of Colonization
Characterization of Chitin Synthesized from Snail Shell
Examining the Long-Term Exposure Effects of Simulated Body Fluid on the Behavior of Chitosan Bonded to Titanium Using Three Biocompatible Solvents
Failure Analysis and Fatigue Properties of a New Generation ▀-based Ti-Nb Alloy and Cp-4 Titanium Osteosynthesis Plates
Functionalization of Dental Titanium Implants for Improved Osteointegration
H-1: Changing in the Elastic Modulus of Ti-10Mo-Zr System Alloys by Specific Heat Treatments
H-2: Correlation between the Presence of Martensitic Phase and Mechanical Properties of Ti-15Mo-xZr Alloys with Potential Orthopedic Application. Alloys with Potential Orthopedic Application
H-4: Structure and Microstructure of Ti-25Ta-Zr Alloys
H-5: Titanium-magnesium Composite for Dental Implants (BIACOM)
Microstructures and Properties of Mg AZ Alloys Subject to High Shear Deformation
Preparation and Characterizations of Nano Composites Based on Biphasic Mixture of Bioactive Ceramics for Biomedical Applications
Rapid Mechanical Assessment of Dental Materials for the Mitigation of Cracks in Natural Teeth
Repelling Biofilm Formation on Dental Materials via Piezoelectric Fillers
Surface Modified Drug Releasing Total Hip Implant
Tailoring of the Mechanical Properties of Alloys of the Ti-Zr-Mo System through Alloying and Heat Treatments
The Effects of Inclusions on the Fatigue Performance of Superelastic Nitinol Fine Wires
Thermomechanical Processing of Beta-Ti Alloys for Load-bearing Implant Applications

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