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Meeting 2018 TMS Annual Meeting & Exhibition
Symposium Biological Materials Science
Presentation Title The Influence of Plastic Deformation Mechanisms on the Collagen Formation in Osteoblast Cells
Author(s) Benay Uzer, Felipe Monte, Kamal R. Awad, Pranesh B Aswath, Venu G. Varanasi, Demircan Canadinc
On-Site Speaker (Planned) Benay Uzer
Abstract Scope In many of biomedical applications the implant might get in direct contact with the bone cells where the osteogenesis needs to be stimulated. If osteoblasts can’t successfully attach on the implant surface the bone might resorb and implant can fail. In the current study the MC3T3 cells were cultured on the 316L stainless steel samples which were deformed up to three strain levels (5, 15 and 25%) to activate plastic deformation mechanisms (slip and twinning) in different volume fractions. The results showed a significant amount of collagen formation on the 25% deformed sample on which slip and twinning mechanisms were activated significantly. Their interaction has also increased the surface energy which would catalyze the deposition of ECM proteins. Overall the manipulation of the material’s microstructure would enhance cell response and as a result long lasting implants could be obtained which would eliminate additional surgical interventions.
Proceedings Inclusion? Planned: Supplemental Proceedings volume

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A Novel Approach of Polymer Grafting on Selective Laser Melted Titanium Alloy Hip Implants for Improved Lubricity and Biocompatibility
A Novel In Vitro Fatigue Test for Biomimetic Implants Made of UHMWPE
Adsorption of Maleic Acid on the Surface of Hydroxyapatite and TiO2: A Pathway Towards Biomaterial Composites
An Anatomic Breast Phantom Mimicking Varying Levels of Radiographic Tissue Density for Translational Investigation of Contrast-enhanced Imaging Using Targeted Nanoparticles
Anchoring Tannic Acid to a Polymeric Backbone - a Novel Burn Wound Treatment
Automatic Shape-based Cell Identification in Arabidopsis Thaliana Cotyledons Using 3D Moment Invariants
Bio-functional Design for Metallic Biomaterials: Cu-bearing Metallic Biomaterials
Bioinspired Polyphenolic Materials: From Biomolecular Phenomena to Applications
Bioinspired Structural and Functional Materials
Brick-and-mortar Alumina Containing a Nickel Compliant Phase Synthesized Using Spark Plasma Sintering
Cryo-drawn of CP Ti: A New Material for Medical Applications
Damage Tolerance in Dental Restorative Materials
Density and Vessel Distribution Interactions in the Impact Resistance of Wood
Design and Testing of Bio-inspired Flexible Armors
Development of Bamboo Based Bio-composites
Effect of Nb and Ta Content on Properties of Ti-(26-35)Nb-(0-6)Ta-7Zr -0.7O
Energy Absorbent Natural Keratin Materials and Bioinspired Designs
Finite Element Simulations and 3D-printed Models of Bone as an Interpenetrating Composite
Fracture and Fatigue Behavior of Silver-cored Drawn Filled Tube Strands for Biomedical Applications
Fracture, Disease and Therapies in Human Bone
Freeze Casting of Bioinspired Porous Ring Structures through Ultrasound Directed Self-assembly
Freeze Casting of Surface-magnetized TiO2 Using a Uniform Magnetic Field to Fabricate Materials Inspired by Bone
From Superhydrophobic to Superhydrophilic: Synthesis of Multifunctional Surfaces Inspired from Carnivorous Plants
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Materials Inspired from Fossils and their Relatives
Mechanics and Toughening Mechanisms of Nacre-inspired Composites
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Modeling Water Absorption and Associated Mechanical Property Changes of Natural Fiber Reinforced Biocomposites
Nanocomposite Heating Probes for Thermoablation of Cancerous Cells
Numerical Investigation of Force Network in 3D Heterogeneous Cellularized ECM
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Optimizing the Structure-property Relationship of Shark Teeth Using Bio-inspired Design
Osteoblast Functions on Bioactive 3D Printed Porous Ti-6Al-4V Scaffolds
Pangolin Armor: Overlapping, Structure, and Mechanical Properties of the Keratinous Scales
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Processing, Microstructure Characterization and Biological Response of Cold Sprayed Biocomposite Coatings
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Silver and Potassium Ion Exchange in Aluminosilicate and Soda Lime Glasses for Antimicrobial Purpose
Spatial Variations in Aging of Teeth about the Arch
Structure and Mechanics of Natural Scales: Inspiration for Novel Flexible Protective Systems
Synergistic Structures from Magnetic Freeze Casting with Surface Magnetized Alumina Particles and Platelets
Synthesis and Evaluation of Polypyrrole-hydroxyapatite Composite Developed through Electro-deposition for Use as Bio-compatible Coating over Metallic Orthopaedic Implant Surfaces
Synthesis of PVA Scaffolds with Gradient Porous Structures by Freeze Casting
The Effect of the Thickness of the Magnetic Biological Patch on the Accumulation Mechanism of Magnetic Particles
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The Study of the Effects of Cancer Drugs on the Structure and Mechanical Properties of Triple Negative Breast Cancer Cells (TNBCs)
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