|About this Abstract
||2018 TMS Annual Meeting & Exhibition
||Surface Interactions in Materials
||Analysis of the Interaction of Serum Albumin with Titanium Dioxide Films Using the Extended Derjaguin-Landau-Verwey-Overbeek (X-DLVO) Theory
||Jonathan M. Schuster, Carlos Schvezov, Mario Rosenberger
|On-Site Speaker (Planned)
Adhesion of serum albumin is a key phenomenon to determine the degree of hemocompatibility of a material. Adhesion of a layer of albumin will passivate the material surface avoiding blood clot formation and platelets activation and then define it as a hemocompatible material. Adhesion is strongly related to the free surface energy and the interaction potentials between a material surface and the albumin molecule in water. The X-DLVO theory is employed to calculate the van der Waals and acid base interaction potential for TiO<SUB>2</SUB> nanofilms produced by the sol-gel method, with an albumin molecule in water. The resultant value of the interaction potential for TiO<SUB>2</SUB> was compared with the calculated values obtained applying the same theory, for pyrolytic carbon and 316L stainless steel. It was found that the acid-base potential was dominant in the interaction potential for the three materials.
||Planned: Supplemental Proceedings volume