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Meeting 2023 TMS Annual Meeting & Exhibition
Symposium Advances in Biomaterials for 3D Printing of Scaffolds and Tissues
Presentation Title Cell-Laden Bioink Circulation-Assisted Inkjet-Based Bioprinting to Mitigate Cell Sedimentation and Cell Aggregation
Author(s) Jiachen Liu, Md Shahriar, Changxue Xu
On-Site Speaker (Planned) Jiachen Liu
Abstract Scope Bioink, as the building block for 3D bioprinting, generally composes of solution of biological materials and living cells. During inkjet bioprinting, since the gravitational force acting on cells is usually greater than the buoyant force provided by the solution of biological materials, cells sediment to form cell aggregates through cell-cell interaction. Cell sedimentation and cell aggregation results in highly nonuniform cell distribution within the bioink reservoir, undermining the printing performance and reliability in several aspects such as nozzle performance, droplet formation, and post-printing cell output, which is recognized as a significant challenge in achieving reliable bioprinting. To alleviate this problem, this study proposes a bioink circulation system to assist inkjet bioprinting without manipulation of bioink properties. Results demonstrate a high effectiveness of the proposed system in mitigating cell sedimentation and cell aggregation, therefore improving the bioprinting performance and reliability.
Proceedings Inclusion? Planned: Supplemental Proceedings volume

OTHER PAPERS PLANNED FOR THIS SYMPOSIUM

Cell-Laden Bioink Circulation-Assisted Inkjet-Based Bioprinting to Mitigate Cell Sedimentation and Cell Aggregation
Development of Propolis Modified Scaffolds for Tissue Engineering
Effects of Corona Treatment on Cellular Attachment and Morphology on Polydimethylsiloxane Micropillar Substrates
Electrohydrodynamic 3D Printing of Aqueous Solutions
Fabrication of Hierarchically Porous 316L Stainless Steel Scaffolds by Freeze Casting and 3D-printed Sacrificial Templating Techniques
High Speed and High-Resolution 3D Printing of Self-healing and Ion-conductive Hydrogels via µCLIP
Investigation of Cell Sedimentation and Cell Aggregation during 3D Bioprinting
Investigation of Cellular Attachment and Morphology on a 3D-printed Curved Micropillar Substrate
K-4: 3D Printing in Thermosensitive Nanoclay-Pluronic F127 Nanocomposite
Processing and Properties of 3D Printed Bioabsorbable Polymer-Metal Composites (PLDL/Mg and PLDL/Zn) for Orthopaedic Applications
The Influence of Printing Orientation on the Mechanical Properties of 3D Printed Parts by Stereolithography (SLA) Process

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