|About this Abstract
||2016 TMS Annual Meeting & Exhibition
||Bio Nano Interfaces and Engineering Applications
||Thermodynamic Characterization of Self-Assembled Peptides on Graphite
||Shohei Tsuchiya, Morio Isoda, Mehmet Sarikaya, Yuhei Hayamizu
|On-Site Speaker (Planned)
Peptides form ordered structures on atomically-flat solid surfaces such as gold (111), mica, and graphite surface, where peptides are possibly templated by the crystal structures of the solid surfaces. The fundamental of the assembly is a key to establish controlled bio-nano interfaces. However, the understanding of thermodynamic characteristics of self-assembled peptides is still limited. In this work, we employed graphite binding peptides (GrBP) and investigated the thermal stability of the ordered structures of peptides. We found that the peptides form two different long-range ordered structures, α-phase and β-phase. Both phases show six-fold symmetry influenced by graphite crystal lattice and one had 22 degrees offset relative to the other in counterclockwise direction. Our time-lapse observations by atomic force microscopy show gradual change of the occupation of each phase over time, indicating that the β-phase is thermodynamically more stable than α-phase.
||Planned: Publication Outside of TMS (Indicate publication title and publisher if known.)