Recently it has been discovered that high entropy contributions to Gibbs free energy can stabilize a new oxide phase with rock salt structure, (Mg, Co, Ni, Cu, Zn)O, with cations randomly distributed over the cation sites.1 Understanding the fundamental properties of this entropy-stabilized oxide (ESO) is of great interest because it opens up possibilities for designing similar materials with well-defined properties for specific applications. Using electronic structure methods within the DFT, the properties of three ESOs (with addition of Li and Sc to the cation-sublattice) are investigated, to see if the empirical parameters may exist that would predict stability of ESOs. Results indicate that lattice constants and, for certain compositions, the Bader charges are transferable from binary and ternary oxides to ESO. The electronic structure analysis of Cu d-states reveals a Jahn-Teller distortion involving O atom displacements. 1Rost, C. M. et al. Entropy-stabilized oxides. Nat. Commun. 6, 8485 (2015).