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Meeting 2016 TMS Annual Meeting & Exhibition
Symposium Bio Nano Interfaces and Engineering Applications
Presentation Title How Do Nano and Microscale Surface Topographies Affect Bacterial Attachment? Designing a New Generation of Antimicrobial Surfaces
Author(s) Benjamin Hatton, Nicolas Lavielle, Dalal Asker
On-Site Speaker (Planned) Benjamin Hatton
Abstract Scope The interaction between bacteria and surfaces is complex and the roles of nano- and micoscale topographies have not been clearly identified. Understanding these relationships is important due to the persistent problem of biomaterial infection rates (often nosocomial), and an increasing problem of antibiotic-resistant strains. I will show examples that shed light on the relationship between nanotopographies and bacterial surface attachment. We have generated nanotopographies using a templated co-assembly method, and with photolithographic etching. An important factor to control bacterial attachment is with surface wettability. Herein we show that non-wetting, superhydrophobic surfaces can precisely allow or prevent bacterial cell attachment. Further, we have that surface microstructures can confine and stabilize a thin lubricant layer, for non-adhesive ‘slippery liquid-infused porous surfaces’ (SLIPS). We have demonstrated the effectiveness of such omniphobic surfaces to effectively prevent bacterial adhesion (30 days, continuous culture) and blood clot adhesion.
Proceedings Inclusion? Planned: Publication Outside of TMS (Indicate publication title and publisher if known.)

OTHER PAPERS PLANNED FOR THIS SYMPOSIUM

An Electrochemical Approach to Control Surface Behavior of Peptides Self-assembling on Graphite
Analytical Study on the Effect of Interface Properties in Brick and Mortar Structured Composites
Bacterial Surface Display for Discovery and Study of Peptide-Directed Material Interfaces
Biological Fabrication of Nanodevices by Protein Supramolecules
Coarse-Grained Modeling of Interaction between Vesicle and Active Rotational Nanotube
Computational Models of Peptide-Surface Interactions Drawn from Bacterial Display Studies: Up Close and Personal
Computational Strategies for Amyoloidogenic Proteins Interacting with Gold NPs
D-1: Elucidation of Sequence-Dependent Structure/Function Relationships for Bimetallic CoPt Nanoparticles
D-2: High Affinity Surface Attachment of F1 Rotary Motors for Nanodevice Fabrication
D-3: Selection of Peptide Aptamer with Ultrahigh Affinity for TiO2 by Combination of Phage Display and Electroporation
D-4: Self-healing in Super-tough Double Network Hydrogels
Design Rules for Molecularly Interfacing Biology and Engineered Solids towards Biomimetic Devices
Designer Self-assembling Peptides for Programming the Bio-material Interface
Effect of Water on the Mechanical Properties of Lignin Carbohydrate Complex
Engineered Interfaces for Dehydrogenase Based Self-Integrated Electrode System
Engineering of Bio-Nano Interfaces on 2D Nanomaterials by Self-Assembled Peptides
Engineering of Biodegradable Boron-Based, Carbon Enriched Nano Fiber in A Hybrid Composite Via DIMOX, Rheocasting and Thixocasting
Gene Expression Profiling of Preosteoblasts on Conventional and Nanostructured Bulk Titanium
Graphene Oxide Reinforced Double Network Hydrogel
Graphite Oxide/Cellulose Composites as Innovative Solid Support Material for DNA Extraction Applications
How Do Nano and Microscale Surface Topographies Affect Bacterial Attachment? Designing a New Generation of Antimicrobial Surfaces
Implantable Magnetic Nanocompsites for Cancer Treatment
Interrogating Bio-Nano Interactions and Enhancing Materials Properties
Mechanism of Specific Recognition of Pt Nanocrystals by Peptides and of their Formation from Seed Crystals
Modeling the Organic-Inorganic Nano Interface in Nanocomposites in Bone Tissue Engineering
Molecular-level Understanding of Peptide Adsorption at Fluid/Solid Interfaces through Molecular Simulation and Its Exploitation in Practise
Nonuniform Breaking of Molecular Bonds, Peripheral Morphology, and Releasable Adhesion by Elastic Anisotropy in Bio-adhesive Contacts
Novel Gyratory Methods for Forming Smart Biointerfaces
Precision Assembly of Biologically Functional Abiotic/Biotic Materials
Recluse Spider's Silk Nanoribbons — a Quasi-2D Protein Material with Outstanding Mechanical and Adhesive Properties
Rules of Induction Towards Chimeric Antimicrobial Peptide Design as Implant Biocoatings
Self-reinforced Fibro-porous 3D Tubes for Vascular Graft Applications
Stimuli Responsive and Reconfigurable Nanoparticle Biointerfaces
Synthesis of Self-cleaning, Transparent and Superhydrophobic/Oleophobic Metal Oxide Coatings by Atmospheric Pressure Plasma Technique
The Structure and Mechanics of the Interfaces within Biological and Bio-inspired Materials
Thermodynamic Characterization of Self-Assembled Peptides on Graphite

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