About this Abstract |
Meeting |
2023 TMS Annual Meeting & Exhibition
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Symposium
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Advances in Magnetic Materials
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Presentation Title |
Incisive Review on Magnetic Iron Oxide Nanoparticles and Their Use in the Treatment of Bacterial Infections
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Author(s) |
Muniratu Maliki, Stanley O. Omorogbe, Ikhazuagbe Hilary Ifijen, Oscar N. Aghedo, Augustine Ighodaro |
On-Site Speaker (Planned) |
Muniratu Maliki |
Abstract Scope |
Magnetic nanoparticles (MNPs) have showed great promise in a variety of biomedical application, including magnetic hyperthermia, improving MRI data, augmenting tissue engineering efforts, and boosting medication delivery to difficult-to-reach microniches. Their integration in diverse illnesses' treatment pathways demonstrates an exponential increase in trend toward the incorporation of innovative biotechnologies in medical and pharmaceutical systems. Clinicians can use superparamagnetic nanoparticles (SPNs) to create a localized thermo-ablative impact that destroys bacterial biofilms. SPNs can also sensitize resistant bacterial cells to antibacterial chemicals by physically disrupting bacterial membranes. IONPS have also enhanced the transport of bactericidal chemicals to microniches, and could thus be used to treat disorders that require therapeutic intervention that must be able to pass through the blood–brain barrier. This Review carried out an incisive study on magnetic iron oxide nanoparticles and their use in the treatment of bacterial infections. This study also focused on the mechanisms underlying the antibacterial action of magnetite iron oxide (IONPS) against microorganisms |
Proceedings Inclusion? |
Planned: |
Keywords |
Biomaterials, Nanotechnology, Magnetic Materials |