| Abstract Scope |
Carbon electrodes offer intriguing properties for neural-interface applications, such as biocompatibility, electrochemical stability, capacitive electrochemical behavior, and fast electron-transfer kinetics. Considered the ideal material for electrochemical detection, carbon has only recently been investigated as electrode material for electrophysiology recordings and micro-stimulation. The integration of carbon in implantable microelectrode arrays (MEAs) would enable the multimodal probing of the brain, elucidating the relationship between electrical and electrochemical signaling and the mechanisms that underpin the efficacy of electrical stimulation for neurotransmission and neuromodulation. This presentation provides an overview of the different strategies we recently adopted for the development of implantable carbon-based MEAs and reports the promising results we obtained in their neural interface applications, including neurochemical sensing and stimulation. Promises and challenges of the use of carbon in the next-generation of neural technology will be discussed. |