About this Abstract |
Meeting |
2022 TMS Annual Meeting & Exhibition
|
Symposium
|
Self-organizing Nano-architectured Materials
|
Presentation Title |
Nanoporous Gold: From an Ancient Material to Biomedical Devices |
Author(s) |
Erkin Seker |
On-Site Speaker (Planned) |
Erkin Seker |
Abstract Scope |
Nanoporous gold (np-Au), produced by a nano-scale self-arrangement process, has mostly attracted attention for catalyst applications due to its high effective surface area, electrical conductivity, and ease of surface functionalization. Surprisingly, biomedical potential of this material has remained largely untapped. I will initially discuss my research group’s efforts to control nano-/micro-scale properties of np-Au and the application of micropatterning techniques for fabricating multiple electrode arrays for high-fidelity neural electrophysiological recordings. In the context of biocompatibility of such devices, I will illustrate how tunable properties of np-Au may be utilized to alleviate adverse biological response to device coatings. To that end, I will specifically focus on np-Au’s drug delivery performance and its interaction with neural tissue as a function of its geometric features and surface chemistry. I will finally illustrate np-Au’s diagnostic potential within an electrochemical platform in detecting and purifying nucleic acid biomarkers in complex biological samples. |
Proceedings Inclusion? |
Undecided |
Keywords |
Biomaterials, Nanotechnology, Thin Films and Interfaces |